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Insert Therapeutics, Inc.
Pasadena, California, United Statesenterothera.com ↗
- Ownership
- Private
- Development stage
- Preclinical
01
Overview
Insert Therapeutics developed a proprietary cyclodextrin-based polymer nanoparticle platform for targeted delivery of small molecule drugs. Its lead program was a camptothecin-polymer conjugate (IT‑101), which showed promising preclinical results in multiple human lymphoma xenograft models. The company’s technology enabled safer and more effective delivery of cytotoxic agents for cancer therapy but did not reach late-stage clinical development before being subsumed by Calando Pharmaceuticals.
- Therapeutic areas
- OncologyEndocrinologyNephrology
- Modalities
- Small molecules (notably camptothecin-polymer conjugates)Polymeric drug delivery systems (cyclodextrin-based nanoparticles)
- Industry
- Biotech
02
Partnerships
No major pharmaceutical partnerships reported prior to acquisition.
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