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Intact Therapeutics

Palo Alto / Redwood City, California, United Statesintacttherapeutics.com ↗

Ownership: Private
Employees: ~4
Development stage: Phase 1

Overview

Intact Therapeutics has developed a biocompatible smart gel formulation that transitions from liquid to viscous gel at body temperature, enabling improved retention and targeted delivery of drugs like mesalamine to inflamed regions in the colon. Preliminary human studies showed better ease of use and retention compared to standard enemas. Early results in patients with ulcerative colitis have been positive regarding healing and usability.

Therapeutic areas: Gastroenterology
Modalities: Advanced materials platform (smart gels)topical/localized drug deliveryrepurposed approved drugs (e.g., mesalamine)
Industry: Biotech

Drug pipeline

1 asset

mesalamine

Phase 1

Indications: Ulcerative colitis, Inflammatory bowel disease

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Evaluating opportunities for co-development partnerships with other entities for new therapies using their drug delivery approach

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