Integral Systems

Integral BioSystems is a specialty drug delivery contract development and manufacturing organization (CDMO) based in Bedford, Massachusetts. The company focuses on the development of complex drug products using proprietary delivery platforms such as O-Sustane for ophthalmics and Nano-M for poorly soluble drugs. Integral BioSystems provides a range of services from initial formulation development and analytical method validation to GLP manufacturing for toxicology studies. Their internal pipeline includes sustained-release treatments for glaucoma, age-related macular degeneration, and various oncology indications. By leveraging expertise in polymer chemistry and nanotechnology, the company aims to improve the bioavailability and therapeutic index of both small molecules and biologics.