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Intero Biosystems has developed GastroScreen, the first stem cell-derived human “mini-gut” organoid that replicates key cell types, spatial architecture, and functions of the human intestine. This platform enables comprehensive preclinical safety and efficacy testing of drugs on a physiologically relevant model before entering clinical trials. The company has demonstrated proof-of-concept for both healthy tissue modeling for toxicity studies and diseased tissue modeling for efficacy screening, such as in intestinal fibrosis.
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