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Intralink-Spine developed an injectable disc stabilization device (Rejuve/IntraLink) based on plant-derived or naturally derived crosslinking compounds that self-polymerize and bind to collagen within the intervertebral disc to mechanically reinforce and stabilize spinal motion segments, targeting degenerative disc disease and chronic low back pain; early pilot/feasibility studies in Malaysia and Australia reported clinically meaningful improvements in pain (VAS) and disability (ODI) in ≥80% of treated patients up to 2 years, with good tolerability and no intraoperative serious adverse events.[3][5][6]
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