Company intelligence / Profile preview
Introgen Therapeutics, Inc.
Austin, Texas, United Statesintrogen.com ↗
- Ownership
- Private
- Development stage
- Other
01
Overview
Introgen was a pioneer in gene therapy for oncology, with its lead product ADVEXIN® targeting the p53 pathway. ADVEXIN showed increased survival and tumor control in recurrent head and neck cancer patients across multiple global Phase I–III trials. The company submitted a BLA to the FDA and an MAA to the EMEA for this indication but faced regulatory setbacks. Financial difficulties led to Chapter 11 bankruptcy filing in late 2008.[1][5]
- Therapeutic areas
- Oncology
- Modalities
- Gene therapy (adenoviral vectors)Molecular therapeuticsImmunotherapiesVaccines[8][4]Nano-particle tumor suppressor therapies[8]
- Industry
- Biotech
02
Drug pipeline
6 assets5 more assets in the full pipeline.
03
Partnerships
Aventis Pharma SA invested $25 million via preferred shares purchasecollaborations with National Institutes of Health/NCIacademic partnerships with University of Texas M.D. Anderson Cancer Center, Columbia University.[2][4]
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