Company intelligence / Profile preview

Introgen Therapeutics, Inc.

Austin, Texas, United Statesmedia.corporate-ir.net ↗
Ownership
Private
Development stage
Phase 3
01

Overview

Introgen was a pioneer in gene therapy for oncology, with its lead product ADVEXIN® targeting the p53 pathway. ADVEXIN showed increased survival and tumor control in recurrent head and neck cancer patients across multiple global Phase I–III trials. The company submitted a BLA to the FDA and an MAA to the EMEA for this indication but faced regulatory setbacks. Financial difficulties led to Chapter 11 bankruptcy filing in late 2008.[1][5]

Therapeutic areas
Oncology
Modalities
Gene therapy (adenoviral vectors)Molecular therapeuticsImmunotherapiesVaccines[8][4]Nano-particle tumor suppressor therapies[8]
Industry
Biotech
02

Drug pipeline

6 assets

Ad5CMV-p53

2

5 more assets in the full pipeline.

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03

Partnerships

Aventis Pharma SA invested $25 million via preferred shares purchasecollaborations with National Institutes of Health/NCIacademic partnerships with University of Texas M.D. Anderson Cancer Center, Columbia University.[2][4]

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