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Iscotec AB is a Swedish biotechnology company specializing in the development and commercialization of vaccine response enhancers and adjuvants. The company is best known for its pioneering work on immunostimulating complexes (ISCOMs) and ISCOMATRIX, which are cage-like nanoparticle adjuvants composed of saponins (specifically Quil A fractions), cholesterol, and phospholipids. These adjuvants are designed to enhance both humoral and cellular immune responses, including cytotoxic T lymphocyte (CTL) activation, making them highly valuable for prophylactic and therapeutic vaccines. Acquired by CSL Limited, Iscotec's technology has been widely utilized in clinical trials for various infectious diseases and cancer vaccines.
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