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ISTA Pharmaceuticals was a leading US-based specialty pharmaceutical company focused on ophthalmology. It marketed several FDA-approved products for eye diseases including Bromday/Xibrom, Bepreve, Istalol, and Vitrase. At the time of its acquisition by Bausch + Lomb in June 2012 for $500 million, it was the third-largest branded prescription eye-care business in the US with an expanding portfolio targeting both approved indications and late-stage pipeline assets for dry eye, ocular inflammation/pain, and nasal allergies. The company had approximately $150 million in annual sales at acquisition[6][7].
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