Company intelligence / Profile preview

Istesso

United Kingdomistesso.co.uk ↗
Ownership
Private
Development stage
Other
01

Overview

Istesso develops first-in-class small molecule drugs that harness the body’s natural adaptive repair mechanisms to treat chronic diseases by repairing damaged tissue rather than just controlling symptoms. Their lead candidate, leramistat, has shown promising results in repairing bone/joint damage in RA without immunosuppression and also targets lung scarring in IPF. Leramistat has received FDA Fast Track and Orphan Drug Designation for IPF. The company’s approach represents a novel paradigm shift from disease management to programmed disease resolution.

Therapeutic areas
OtherImmunologyPulmonologyRheumatology
Modalities
Small molecules (noted as "once-daily pill" and drug-like compounds)
Industry
Biotech
02

Drug pipeline

3 assets

Leramistat

2

2 more assets in the full pipeline.

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