Company intelligence / Profile preview

Jacobio Pharmaceuticals

Beijing, Beijing, Chinajacobiopharma.com ↗
Ownership
Private
Employees
~257
Development stage
Other
01

Overview

Jacobio Pharmaceuticals is advancing glecirasib (KRAS G12C inhibitor) in pivotal Phase 3 trials for NSCLC (and combinations) and basket registration Phase 2 trials for pancreatic and other solid tumors. Its SHP2 inhibitor JAB-3312 is globally in pivotal studies, and early-stage pipeline assets (e.g., pan-KRAS, p53 activators, BET inhibitor) have entered clinical trials. Several programs have received regulatory priority review designation in China and US IND approvals, with combinations and dose expansion ongoing. Jacobio leverages proprietary allosteric and antibody-drug conjugate platforms for undruggable cancer targets.[1][2][4][6][8][9]

Therapeutic areas
OncologyHematology
Modalities
Small moleculeMonoclonal antibodyAntibody-drug conjugateAntibody oligonucleotide conjugateImmune-stimulating antibody conjugate
Industry
Biotech
02

Drug pipeline

19 assets

glecirasib

3

18 more assets in the full pipeline.

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03

Partnerships

AbbVieMerck (clinical collaboration for JAB-BX102 + pembrolizumab)Shanghai Allist Pharmaceuticals

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