Japan Bio

Japan Bio Science Laboratory (JBSL) is a specialized biotechnology company focused on the research, development, and manufacturing of functional food ingredients and bio-active compounds. The company is globally recognized as the pioneer of Nattokinase, specifically its proprietary NSK-SD brand, which is a potent fibrinolytic enzyme derived from fermented soybeans. Beyond cardiovascular health, JBSL develops specialized extracts such as Ashitaba (containing unique chalcones) and sesame lignans targeted at metabolic and liver health. Headquartered in Osaka, Japan, with a significant international presence, the company provides clinically-backed ingredients to the pharmaceutical and nutraceutical industries. JBSL maintains a strong emphasis on fermentation technology and rigorous safety standards, including non-vitamin K2 certification for its flagship enzyme products.