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Jasper's lead program, briquilimab, demonstrated positive responses in earlier dose cohorts in chronic spontaneous urticaria and chronic inducible urticaria, but recent data were confounded by an inactive drug lot, resulting in lower-than-expected responses in key Phase 1/2 cohorts and a halt to their asthma and severe combined immunodeficiency programs. New cohorts were initiated to determine robust dosing and resume progress in urticaria[2][3][4][6].
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