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Joyo Pharma is advancing JYP0322, a ROS1 inhibitor, into a pivotal phase 3 trial in China for second-line ROS fusion-positive NSCLC post prior ROS1-TKI, with phase 1 ORR of 55% reported at AACR[5]. Other programs include phase 3 in idiopathic pulmonary fibrosis and phase 2 in oncology[8].
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