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Joyo researches and develops innovative small-molecule drugs for tumors, autoimmunity and infectious diseases, with one project in phase 3 clinical trials, six projects/indications in phase 2, and multiple programs in phase 1 or preclinical stages.[1][3] Its ROS1 inhibitor JYP0322 showed a 55% objective response rate in a phase 1 NSCLC trial and is moving into a pivotal phase 3 study, while its pan-RAS(ON) inhibitor JYP0015 was out-licensed ex-China to Erasca, which is advancing it in phase 2 for advanced solid tumors with RAS mutations.[1][2][3]
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