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JV Biotherapeutics is a preclinical-stage biotechnology company focused on developing novel biologics for the treatment of cancer cachexia and metabolic diseases. The company's primary research centers on the Growth Differentiation Factor 15 (GDF15) pathway, aiming to modulate its activity to address severe weight loss and muscle wasting in cancer patients. By leveraging expertise in protein engineering, JV Biotherapeutics is designing therapies that can either inhibit or mimic GDF15 signaling depending on the clinical indication. Their lead programs are currently undergoing optimization and early-stage validation to support future IND filings.
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