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Kadmon

Ownership: Private
Employees: ~100
Development stage: Commercial

Overview

Rezurock™ (belumosudil), a first-in-class oral ROCK2 inhibitor, received FDA approval in July 2021 for chronic graft-versus-host disease after failure of at least two prior lines of systemic therapy. Clinical trials showed a response rate of ~75% with durable benefit. Other pipeline assets include candidates for fibrotic and immune diseases as well as immuno-oncology therapies. The company was acquired by Sanofi in November 2021 and its stock delisted from NASDAQ.[3][6]

Therapeutic areas: PulmonologyCardiovascularMetabolic DisordersRheumatologyImmunologyOncologyInfectious Diseases
Modalities: Small molecules[10]Antibodies[10]Antibody fusion proteins[10]Interferons[10]
Industry: Biotech

Drug pipeline

9 assets

belumosudil

Approved

8 more assets in the full pipeline.

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Partnerships

– BioNova Pharma for KD025/belumosudil development/commercialization in China [5]– Various academic collaborations historically; specifics not detailed in current sources.

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