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Rezurock™ (belumosudil), a first-in-class oral ROCK2 inhibitor, received FDA approval in July 2021 for chronic graft-versus-host disease after failure of at least two prior lines of systemic therapy. Clinical trials showed a response rate of ~75% with durable benefit. Other pipeline assets include candidates for fibrotic and immune diseases as well as immuno-oncology therapies. The company was acquired by Sanofi in November 2021 and its stock delisted from NASDAQ.[3][6]
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