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KAHR’s lead program DSP107, a bispecific, bifunctional fusion protein combining SIRPα and 4-1BBL, has completed a Phase 1/2a trial in third-line microsatellite-stable colorectal cancer with reported improvements in survival, response rate, and disease control rate, and the company is seeking funding for a randomized Phase 2b trial in colorectal cancer.[1][2]
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