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KAI Pharmaceuticals developed selective modulators of protein kinase C isozymes, with a lead compound (KAI‑9803) that completed Phase I/II trials in acute myocardial infarction before being acquired by Amgen in April 2012 for $315 million. The company also worked on therapies for secondary hyperparathyroidism and kidney diseases. Kai BioTech Co., Ltd. is a separate active Korean company focused on radiopharmaceuticals for indications such as dementia and liver cancer.
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