Kalexo Bio

Kalexo is a pre-clinical stage biotechnology company dedicated to engineering biologics that can effectively cross the blood-brain barrier (BBB) to treat central nervous system disorders. Founded by Arnon Rosenthal, a pioneer in neuro-immunology and co-founder of Alector and Rinat Neuroscience, the company is developing a proprietary transport platform to deliver large molecules like antibodies and enzymes into the brain. By significantly enhancing brain uptake, Kalexo aims to unlock the therapeutic potential of biologics for neurodegenerative conditions such as Alzheimer's and Parkinson's disease. The company's technology focuses on overcoming the historical limitations of treating brain diseases where most large molecules fail to reach their targets in sufficient concentrations. Kalexo is headquartered in South San Francisco and is backed by leading life science investors including Foresite Capital.