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KalVista Pharmaceuticals

Cambridge, Massachusetts, United Stateskalvista.com ↗
Ownership
Public · KALV
Employees
~130
Development stage
NDA
01

Overview

Sebetralstat demonstrated positive results in pivotal Phase III clinical trials for on-demand treatment of hereditary angioedema. It offers an oral alternative to injectable therapies and has received Fast Track and Orphan Drug Designations from the FDA. Regulatory filings are underway globally; if approved it will be the first oral on-demand HAE therapy worldwide.

Therapeutic areas
ImmunologyCardiovascular
Modalities
Small molecules (oral protease inhibitors, specifically kallikrein inhibitors)
Industry
Biotech
02

Drug pipeline

11 assets

sebetralstat

Approved

10 more assets in the full pipeline.

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03

Partnerships

Kaken Pharmaceutical Co., Ltd. – exclusive commercialization partner for sebetralstat in Japan; includes upfront/milestone payments and royalties based on salesDRI Healthcare Trust – synthetic royalty financing agreement related to sebetralstat future revenues
04

Financials

Market cap
$1.4B
Total revenue
$59.9M
Enterprise value
$1.4B

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