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Karyon Bio is a preclinical-stage biotechnology company focused on developing novel small molecule therapeutics for hormone-driven cancers. The company specializes in targeting protein-protein interactions between nuclear receptors and their oncogenic co-regulators, a space previously considered undruggable. Their lead research programs target the interaction between the androgen receptor and PELP1 to treat castration-resistant prostate cancer. By utilizing a proprietary peptidomimetic-based discovery platform, Karyon Bio aims to provide new treatment options for patients who have exhausted standard hormonal therapies.
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