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Kerberos Biopharmaceuticals is a pre-clinical stage biotechnology company spun out of the Drexel University College of Medicine. The company focuses on developing novel therapeutics to prevent and treat metastatic cancer, specifically targeting the chemokine receptor CX3CR1 (fractalkine receptor) and its role in tumor progression and metastasis. Its lead program, JMS-17-2, is a potent small-molecule antagonist of CX3CR1 designed to impair the lodging of circulating tumor cells to the skeleton and soft-tissue organs. Although the company demonstrated promising results in animal models of metastatic breast cancer, it has since become inactive (deadpooled).
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