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Company intelligence / Profile preview
Kineta has developed a pipeline focused on next-generation immunotherapies targeting mechanisms of cancer immune resistance. Its lead asset, KVA12123—a VISTA-blocking antibody—is in Phase 1/2 clinical trials for advanced solid tumors. Early results from the VISTA101 trial show partial responses and stable disease with no dose-limiting toxicities observed. The company also has a preclinical anti-CD27 agonist mAb program. In early 2024, Kineta underwent significant restructuring due to funding shortfalls and began exploring strategic alternatives, including a pending acquisition by TuHURA Biosciences.
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