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Kinnate’s lead asset exarafenib (KIN-2787), a selective pan-RAF inhibitor, is in Phase 1/1b trials for advanced solid tumors driven by BRAF/NRAS alterations; early clinical data focus on safety, tolerability, and pharmacodynamics. KIN-3248 targets FGFR2/3, also in early-stage development. Additional preclinical assets include MEK and c-MET inhibitors.
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