Klotho Sciences

Klotho Sciences is a biotechnology company focused on the development of therapies based on the Klotho protein, a key regulator of aging and metabolism. The company was founded by Dr. Makoto Kuro-o, who originally discovered the Klotho gene and its role in longevity. Klotho Sciences aims to treat age-related diseases, including chronic kidney disease and neurodegenerative conditions, by restoring levels of the Klotho protein. Their lead programs utilize recombinant Klotho protein to address the systemic decline of this hormone seen in aging populations. The company's research leverages deep expertise in the molecular mechanisms of mineral metabolism and oxidative stress.