Konan Chemical Manufacturing

Konan Chemical Manufacturing, commonly known as Konan Kako, is a Japanese contract development and manufacturing organization (CDMO) focused on active pharmaceutical ingredients (APIs) and intermediates. Established in 1953, the company offers specialized chemical synthesis services, including high-potency API (HPAPI) production and complex reactions like halogenation and high-pressure synthesis. Operating under stringent GMP standards, Konan Kako supports pharmaceutical clients from early-stage process development to large-scale commercial manufacturing. The company is headquartered in Osaka and maintains significant production facilities at its Yashiro Plant in Hyogo Prefecture. Its expertise in handling hazardous materials and complex chemistry makes it a key partner for small molecule drug developers globally.