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Kymera Therapeutics

Watertown, Massachusetts, United Stateskymeratx.com ↗
Ownership
Public · KYMR
Development stage
Phase 1
01

Overview

Kymera has advanced multiple first-in-class oral targeted protein degraders into clinical development. KT‑474/ SAR444656 targets IRAK4 for immune-inflammatory diseases and has entered Phase 2 trials with Sanofi as a partner. KT‑621 targets STAT6 for allergic/inflammatory diseases and has shown promising preclinical results. The company’s oncology pipeline includes KT‑253 targeting MDM2 in AML with orphan drug designation from the FDA. Additional programs target hematological malignancies via IRAKIMiD compounds.[3][4]

Therapeutic areas
OncologyImmunologyDermatology
Modalities
Targeted protein degraders (small molecules)[1][2][4]
Industry
Biotech
02

Drug pipeline

15 assets

KT-621

2

14 more assets in the full pipeline.

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03

Partnerships

Sanofi – partnered on development of KT‑474/SAR444656 for immune-inflammatory diseases with profit-sharing in the US and royalties ex-US[3]NEOsphere Biotechnologies – partnership to identify new molecular glue targets[4]
04

Financials

Market cap
$9.6B
Total revenue
$65M
Enterprise value
$9B

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