Company intelligence / Profile preview

L.E.A.F. Pharmaceuticals

Woburn, Massachusetts, United Statesleafpharmaceuticals.com ↗

Ownership: Private
Development stage: Preclinical

Overview

As of October 2018, L.E.A.F. Pharmaceuticals received positive US FDA feedback for four lead anticancer drugs—LEAF‑1401, LEAF‑1701, LEAF‑1702, and LEAF‑1703—with guidance to move all four into a single first-in-human Phase 1 clinical trial. One candidate may be eligible for registration via the FDA’s accelerated 505(b)(2) pathway. The company has filed over 55 patent applications since its founding in August 2014. No published clinical results yet; programs are at or near IND-enabling/early clinical stage.

Therapeutic areas: Oncology
Modalities: Small molecules (specifically onco-immuno antimetabolites)
Industry: Biotech

Drug pipeline

4 assets

LEAF-1701

Preclinical

3 more assets in the full pipeline.

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Partnerships

Contract manufacturing organization partnership for production of investigational drug substance(s)

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