Company intelligence / Profile preview

LadRx

Los Angeles, California, United Statesladrxcorp.com ↗
Ownership
Public · LADX
Development stage
Preclinical
01

Overview

LadRx’s lead clinical asset was aldoxorubicin—a rationally engineered cytotoxic that delivers doxorubicin directly to tumors using albumin-binding. Aldoxorubicin has shown lower cardiotoxicity and promising efficacy in Phase II trials for advanced soft tissue sarcoma. The company’s next-generation candidate LADR‑7 has been manufactured under GMP and aims for IND filing in late 2024. The company previously outlicensed assets like arimoclomol and aldoxorubicin but recently regained rights to aldoxorubicin after terminating its license with ImmunityBio.

Therapeutic areas
OncologyNeurology
Modalities
Small molecule
Industry
Biotech
02

Drug pipeline

10 assets

bafetinib

2

9 more assets in the full pipeline.

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03

Partnerships

ImmunityBio/NantCell Inc. (previous licensee of aldoxorubicin; agreement now terminated)Orphazyme A/S/Zevra Inc. (arimoclomol licensee—royalty/milestone rights transferred to XOMA Corp.)XOMA Corporation (holds royalty/milestone rights on certain assets)
04

Financials

Market cap
$5.4K
Total revenue
$0
Enterprise value
$-201.5K

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