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LB Pharmaceuticals’ lead candidate LB-102, a novel derivative of amisulpride, demonstrated statistically significant improvement in schizophrenia symptoms versus placebo in a 359-patient Phase 2 trial. The Phase 3 trial for schizophrenia is scheduled to start in early 2026, with an additional Phase 2 study in bipolar depression planned. Side effects in Phase 2 were manageable, and the company aims for an NDA submission in 2028.
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