Company intelligence / Profile preview

Leaderna Therapeutics

Ownership
Private
Development stage
Phase 1
01

Overview

Leaderna Therapeutics is a spin-off from HitGen Inc., focused on developing advanced RNA therapies. Its lead asset Lipisense® targets ANGPTL4 to treat lipid metabolism disorders and has reached Phase II trials for hypertriglyceridemia. The company has partnered with Lipigon Pharmaceuticals to develop and commercialize Lipisense® in Greater China, with promising early clinical results and significant deal value ($91 million). Another pipeline program targets AGT for essential hypertension.

Therapeutic areas
Metabolic DisordersCardiovascularEndocrinology
Modalities
Antisense oligonucleotides (ASO)Oligonucleotide therapiesRNA-based drugs
Industry
Biotech
02

Drug pipeline

3 assets

GalNAc-siRNA targeting ANGPTL4

Preclinical

2 more assets in the full pipeline.

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03

Partnerships

Lipigon Pharmaceuticals AB – development/commercialization partnership for Lipisense®, covering Greater China region; deal valued up to $91 million USD.

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