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Legend Labz

Somerset, New Jersey, United Stateslegendlabz.com ↗

Ownership: Private
Employees: ~1800
Development stage: Preclinical

Overview

Legend Biotech has achieved commercial success with Carvykti, a BCMA-targeted CAR-T cell therapy for multiple myeloma, showing significant survival benefits including a 59% reduction in risk of progression or death as second-line treatment. The company’s pipeline includes next-generation cell therapies leveraging its proprietary T-Charge platform, with ongoing expansion into solid tumor indications through major partnerships with Novartis and Johnson & Johnson/Janssen. Recent clinical data highlight durable responses and improved overall survival in relapsed/refractory multiple myeloma patients[1][10].

Therapeutic areas: Oncology
Modalities: CAR-T cell therapyT-cell receptor (TCR-T) therapyNatural killer (NK) cell-based immunotherapyCell therapy (general)
Industry: Biotech

Drug pipeline

1 asset

MBX200

Pre-clinical

Indications: Muscle growth, Athletic performance

Partnerships

Johnson & Johnson/Janssen – co-development/commercialization of Carvykti [8]Novartis – $100M upfront deal for access to solid tumor-directed CAR-Ts using the T-Charge platform [10]Multiply Labs – robotics/automation partnership to streamline manufacturing [6]Breakthrough Properties – R&D facility collaboration [6]

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