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Legend Biotech received FDA approval for ciltacabtagene autoleucel (CARVYKTI®) in relapsed/refractory multiple myeloma in 2022; latest 5-year survival data presented at ASCO 2025 are described as groundbreaking. CARVYKTI demonstrates unprecedented efficacy in heavily pre-treated patients and is marketed primarily in partnership with Janssen Biotech. Expanding pipeline includes novel CAR-T assets in solid tumors (DLL3).
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