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LIfT BioSciences has developed a first-in-class allogeneic neutrophil-based cell therapy platform. Their lead product uses Immunomodulatory Alpha Neutrophils (IMANs) derived from hematopoietic stem cells to directly kill tumor cells and modulate the immune system. Preclinical data show potent anti-tumor activity and reprogramming of the tumor microenvironment. The company is preparing for its first Phase 1 trial in solid tumors such as pancreatic, lung, and gastric cancers.
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