Company intelligence / Profile preview

Lineage Cell Therapeutics

Carlsbad, California, USAlineagecell.com ↗
Ownership
Public · LCTX
Development stage
Phase 2
01

Overview

OpRegen® has shown promising results in a Phase 2a trial under collaboration with Roche/Genentech targeting geographic atrophy in AMD patients. The program has received RMAT designation by FDA. OPC1 is in early phase clinical trials showing initial safety and efficacy signals for spinal cord injury treatment. VAC2 is undergoing Phase I trials as an immuno-oncology candidate[5][6][10].

Therapeutic areas
OphthalmologyOncologyNeurology
Modalities
Allogeneic ("off-the-shelf") cell therapies derived from pluripotent stem cellsRetinal pigment epithelial cellsOligodendrocyte progenitor cellsAuditory neuronal progenitor cellsPhotoreceptor neural cellsDendritic cell immunotherapies
Industry
Biotech
02

Drug pipeline

14 assets

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Approved

13 more assets in the full pipeline.

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03

Partnerships

Roche / Genentech collaboration on OpRegen® retinal therapy program[4][5]License agreement with Eterna Therapeutics Inc for gene-edited hypoimmune iPSC lines[4]
04

Financials

Market cap
$254.3M
Total revenue
$1.1M
Enterprise value
$205.8M

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