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LinXis Biopharmaceuticals

Amsterdam, North Holland, Netherlandslinxispharmaceuticals.com ↗
Ownership
Private
Employees
~20
Development stage
Phase 1
01

Overview

LinXis has entered a pivotal clinical imaging study to validate its lead Fibrobody® tracer’s ability to target active fibrotic tissue in patients. This will inform patient selection and de-risk subsequent development of their drug-conjugate therapeutics. Preclinical data support selective targeting of activated myofibroblasts across multiple organs. No late-stage efficacy results yet disclosed.[1][2][5][6] The company recently received a TKI–PPP grant to advance its pulmonary fibrosis program.[1] Academic collaboration ongoing with Amsterdam University Medical Center.[6] Historic licensing deal with APO-T B.V. on ADC/linker tech for oncology applications.[8]

Therapeutic areas
GastroenterologyPulmonologyMetabolic DisordersOncologyRare Diseases
Modalities
Protein-based drug conjugates (Fibrobody®)Antibody-drug conjugates (historically, via linker technology)siRNA conjugates (preclinical)Diagnostic imaging agents (protein tracer conjugates)Cytotoxic payloads for oncology applications (Oncobody® program)
Industry
Biotech
02

Drug pipeline

6 assets

Fibrobody siRNA Conjugate

Preclinical

5 more assets in the full pipeline.

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