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LinXis Biopharmaceuticals
- Ownership
- Private
- Employees
- ~20
- Development stage
- Phase 1
Overview
LinXis has entered a pivotal clinical imaging study to validate its lead Fibrobody® tracer’s ability to target active fibrotic tissue in patients. This will inform patient selection and de-risk subsequent development of their drug-conjugate therapeutics. Preclinical data support selective targeting of activated myofibroblasts across multiple organs. No late-stage efficacy results yet disclosed.[1][2][5][6] The company recently received a TKI–PPP grant to advance its pulmonary fibrosis program.[1] Academic collaboration ongoing with Amsterdam University Medical Center.[6] Historic licensing deal with APO-T B.V. on ADC/linker tech for oncology applications.[8]
- Therapeutic areas
- GastroenterologyPulmonologyMetabolic DisordersOncologyRare Diseases
- Modalities
- Protein-based drug conjugates (Fibrobody®)Antibody-drug conjugates (historically, via linker technology)siRNA conjugates (preclinical)Diagnostic imaging agents (protein tracer conjugates)Cytotoxic payloads for oncology applications (Oncobody® program)
- Industry
- Biotech
Drug pipeline
6 assets5 more assets in the full pipeline.
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