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LittDD Medicines is advancing a pipeline of orally available small molecules that target multiple critical tumor growth and survival pathways. Their lead asset, LIT0814, is in Phase 1 clinical trials for esophageal cancer and CRC. Another candidate, LIT0922, is an mTORC2 selective inhibitor entering clinical trials by the end of 2024. The company’s approach focuses on biomarker-selected patient populations to improve efficacy and reduce resistance
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