Loeb Holding Corporation

Loeb Holding Corporation is a private investment firm and merchant bank based in New York that specializes in venture capital and private equity, with a strong focus on the healthcare and life sciences sectors. The firm traces its origins to the legacy of Loeb, Rhoades & Co. and currently operates as a family office and investment vehicle for the Kempner and Loeb families. It is particularly well-known in the biotechnology community for its role as the founding and lead investor in Intercept Pharmaceuticals, a company that achieved significant success in developing treatments for chronic liver diseases. Loeb Holding employs a 'company-building' approach, providing not only capital but also strategic and operational guidance to its portfolio companies over long-term horizons. Its investment portfolio includes a diverse range of companies in drug development, healthcare information technology, and digital health services, such as Aetion and Cureatr. The firm continues to be an active participant in the healthcare innovation ecosystem, leveraging its deep industry expertise to identify and scale high-impact medical technologies.