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Loema is a French biotechnology company focused on developing first-in-class therapies for rare diseases, specifically Loeys-Dietz Syndrome (LDS). Founded in 2022 by former Genfit executives, the company is headquartered in Lille and targets the TGF-beta signaling pathway to treat connective tissue disorders. Its lead program, LOE-001, is an oral small molecule therapeutic aimed at preventing aortic aneurysms and other vascular complications in LDS patients. Loema's approach combines deep biological insights with a focused development strategy to address high unmet medical needs in the rare disease space.
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