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Lyndra Therapeutics

Watertown, Massachusetts, United Stateslyndra.com ↗

Ownership: Private
Development stage: Phase 3

Overview

Lyndra’s lead candidate—oral weekly risperidone—achieved a phase III efficacy win in adult patients with schizophrenia and schizoaffective disorder as of January 2024. The study was stopped early due to positive interim results showing comparable efficacy to daily Risperdal. A phase III safety trial will begin in the first half of 2025. The LYNX platform has demonstrated clinical proof-of-concept across five therapeutic areas using over twenty-five APIs.

Therapeutic areas: Infectious DiseasesPsychiatryWomen's Health
Modalities: Small molecules (oral formulations)Potential for peptides and other APIs (platform supports multiple modalities)
Industry: Biotech

Drug pipeline

4 assets

risperidone

Phase 3

Indications: Schizophrenia, Bipolar 1 disorder

3 more assets in the full pipeline.

Partnerships

Thermo Fisher Scientific – strategic collaboration for research & commercial manufacturing services leveraging Thermo Fisher’s CDMO/CRO capabilities including commercial-scale production of LYNX-based products.

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