sirolimus
Phase 1- Indications
- Diabetic macular edema, Wet age-related macular degeneration
Company intelligence / Profile preview
MacuSight developed a proprietary formulation of sirolimus (rapamycin) for ocular diseases. The company completed Phase I trials for DME and was initiating Phase II trials for DME and wet AMD as of 2008-2009. The drug demonstrated multiple mechanisms of action including immunosuppressive, anti-angiogenic, anti-migratory, anti-proliferative, anti-fibrotic and anti-permeability activity.
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