Company intelligence / Profile preview

Madrigal Pharmaceuticals

West Conshohocken, Pennsylvania, United Statesmadrigalpharma.com ↗
Ownership
Public · MDGL
Employees
~528
Development stage
Other
01

Overview

Madrigal Pharmaceuticals developed resmetirom (brand name Rezdiffra), a first-in-class oral small-molecule thyroid hormone receptor beta agonist. In March 2024, it became the first FDA-approved treatment for MASH with moderate to advanced liver fibrosis. The pivotal Phase 3 MAESTRO-NASH trial demonstrated significant efficacy and safety results published in The New England Journal of Medicine. The company has since launched Rezdiffra commercially in the US.

Therapeutic areas
GastroenterologyCardiovascularMetabolic Disorders
Modalities
Small molecule
Industry
Biotech
02

Drug pipeline

11 assets

resmetirom

Approved

10 more assets in the full pipeline.

03

Partnerships

Evonik Corporation (commercial supply agreement for manufacturing resmetirom API)
04

Financials

Market cap
$9.2B
Total revenue
$958.4M
Enterprise value
$8.6B

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