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Mammoth Group

Brisbane, California, United States
Ownership
Private
Employees
~200
Development stage
Other
01

Overview

Mammoth Biosciences is a biotechnology company focused on leveraging CRISPR technology to develop a new generation of diagnostics and therapeutics. Co-founded by Nobel laureate Jennifer Doudna, the company utilizes a diverse toolbox of CRISPR proteins, including Cas12, Cas13, Cas14, and CasPhi, to enable high-precision genome editing and rapid molecular detection. Their therapeutic efforts focus on "ultra-compact" CRISPR systems that can be more easily delivered to target tissues via viral or non-viral vectors, potentially overcoming the delivery limitations of traditional Cas9 systems. Mammoth has established significant partnerships with industry leaders like Bayer, Vertex, and Regeneron to advance its pipeline in liver disease and other therapeutic areas. The company is currently in the pre-clinical stage for its therapeutic programs while having successfully deployed diagnostic solutions through its DETECTR platform.

Therapeutic areas
OncologyInfectious DiseasesRare DiseasesGastroenterology
Modalities
CRISPR-based therapyGene therapyLipid nanoparticle delivery therapyDiagnostic
Industry
Biotech
02

Partnerships

BayerVertex PharmaceuticalsRegeneronGSKAgilent TechnologiesBechtel

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