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Mango Therapeutics is an early-stage biotechnology company focused on developing next-generation small molecule modulators of the dopamine transporter (DAT). The company aims to address limitations of current stimulant medications used for neuropsychiatric conditions by creating therapies with improved safety profiles and reduced potential for abuse. Their lead programs target indications such as attention deficit hyperactivity disorder (ADHD) and binge eating disorder. By leveraging structural biology and advanced medicinal chemistry, Mango Therapeutics seeks to optimize the kinetics and selectivity of DAT inhibition.
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