Company intelligence / Profile preview

Manifold Bio

Allston, Massachusetts, United Statesmanifold.bio ↗
Ownership
Private
Employees
~50
Development stage
Preclinical
01

Overview

Manifold Bio has developed a proprietary high-throughput in vivo drug design platform using protein barcoding ("mCodes") that enables simultaneous testing of hundreds of therapeutic candidates within living systems. The company’s approach allows rapid optimization and selection of targeted biologic drugs with improved efficacy and safety profiles. Internal programs are focused on oncology and neuromedicine; no clinical results have been published yet as the pipeline remains preclinical.

Therapeutic areas
OncologyNeurology
Modalities
Protein therapeutics (including antibodies, cell engagers, ADCs)Engineered biologics (shuttles for tissue targeting)Conditionally activated biologicsHalf-life extension technologiesSubcutaneous administration platforms
Industry
Biotech
02

Drug pipeline

4 assets

MAN-03

Preclinical

3 more assets in the full pipeline.

03

Partnerships

Open to collaborations leveraging their mDesign™ platform; specific partners not named publicly yet.Investors include Triatomic Capital, Section32, FPV Ventures, Horizons Ventures, Tencent, Playground Global among others.

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