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MannKind Corporation’s lead product, Afrezza (inhaled insulin), is FDA-approved and commercially available for diabetes. Afrezza is a rapid-acting insulin that peaks 12–15 minutes after inhalation and clears the body in 2–3 hours, delivered via a breath-powered inhaler and pre-metered cartridges[1]. The company has explored Technosphere-based formulations for other therapeutic proteins, but Afrezza remains its only approved drug. Clinical results for Afrezza have demonstrated rapid pharmacokinetics, but commercial uptake has been modest[1].
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