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MantiCore Pharmaceuticals was a biotechnology company based in Salt Lake City, Utah, focused on the development of novel oncology therapeutics. Founded in 1995 as a spin-off from the University of Utah, the company specialized in the synthesis of complex small molecules and targeted drug delivery systems. Its research primarily centered on triptolide analogs and cobalamin (Vitamin B12) conjugates designed to inhibit the TFIIH complex and treat various forms of cancer. Led by industry veterans Ned Weinshenker and Gerald T. Simmons, MantiCore was a key player in the early Utah life sciences cluster before becoming inactive in the mid-2000s.
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