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Marinus Pharmaceuticals

Radnor, Pennsylvania, United Statesmarinuspharma.com ↗

Ownership: Public · MRNS
Development stage: Commercial

Overview

Marinus Pharmaceuticals developed ZTALMY® (ganaxolone), an FDA-approved oral suspension for seizures associated with CDKL5 deficiency disorder. The company continues to advance ganaxolone in IV and oral formulations targeting additional seizure disorders such as status epilepticus and tuberous sclerosis complex. Recent clinical results include pivotal trials in refractory status epilepticus and tuberous sclerosis complex, with topline data readouts expected or recently announced. The acquisition by Immedica strengthens the global reach of these therapies.

Therapeutic areas: Rare DiseasesNeurology
Modalities: small molecules (notably neuroactive steroids)
Industry: Biotech

Drug pipeline

2 assets

ganaxolone

Commercial

Indications: Status epilepticus, Tuberous sclerosis complex, CDKL5 deficiency disorder

1 more asset in the full pipeline.

Partnerships

Tenacia Biotechnology for CNS disorders development in China/Asia-Pacific regionSagard Healthcare Partners revenue interest financing agreement related to U.S. net sales of ganaxolone/ZTALMY®

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