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The Mediterranean Centre for Gene Therapy (MCGT) is a specialized biotechnology organization focused on the development and clinical application of gene therapies for inherited blood disorders. Based in Sicily, the center operates as a hub for translational research, bridging the gap between laboratory discovery and clinical treatment for conditions prevalent in the Mediterranean region, such as beta-thalassemia. MCGT utilizes advanced viral vector technologies, including lentiviral and adeno-associated virus (AAV) systems, to deliver functional genes to patient cells. The center is recognized for its clinical trial infrastructure and its role in pioneering gene-addition strategies for hemoglobinopathies.
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